Affinity Capillary Electrophoresis in Pharmaceutics and Biopharmaceutics
Reinhard H. H. Neubert,Hans-Hermann Ruttinger
ISBN: 9780824709518
Vydavatelství: Taylor & Francis
Rok vydání: 2003
Vazba: Hardback
Počet stran: 384
Dostupnost: Skladem
Původní cena: 3 947 Kč
Výstavní cena:
2 763 Kč(t.j. po slevě 30%)
(Cena je uvedena včetně 10% DPH)
Katalogová cena: 99 GBP
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This reference presents the most recent breakthroughs and techniques in affinity capillary electrophoresis (ACE) to measure and determine the physicochemical and thermodynamic parameters of drug compounds. The authors offer strategies to explore and characterize interactions between drugs, drug vehicles, and biological membranes to facilitate developments in controlled drug delivery and targeting. The book contains current applications and procedures to identify binding constants between drugs, biological structures, proteins, nucleic acids, and plasmids, increase drug bioavailability, enhance the permeability, solubility, strength, and function of drug formulations, examine protein-protein exchanges and reactions, and calculate pKa values.