Epstein M. - Angiotensin II Receptor Antagonists

Angiotensin II Receptor Antagonists

Epstein M.

ISBN: 1560534532
Vydavatelství: Hanley & Belfus
Rok vydání: 2001
Dostupnost: Na objednávku

Původní cena: 0 Kč
Cena: Na vyžádání

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The recent development of several new, non-peptide, orally active angiotensin II receptor antagonists is revolutionizing the treatment of patients with hypertension and various cardiovascular disorders. In this book experts review the current state of angiotensin II antagonists and survey the progress of these diverse applications. Issues relating to angiotensin II and their receptors are examined in relation to their effects on the kidney, non-diabetic renal disease, heart disease, diabetes mellitus, and various other disorders. The combination of AT1 receptor antagonists with other antihypertensive agents is reviewed in depth. The clinical attributes of these drugs are complemented by in-depth reviews of the physiology and pharmacology of angiotensin II peptides. The authors present the most recent findings in ligand recognition, activation, signal coupling, desensitization and functional alterations of vessels, especially small arteries, in patients with hypertension.