Bottomley K. - Metalloproteinases as Targets for Anti-Inflammatory Drugs

Metalloproteinases as Targets for Anti-Inflammatory Drugs

Bottomley K.

ISBN: 3764358564
Vydavatelství: Birkauser
Rok vydání: 1999
Dostupnost: Na objednávku

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Cena: Na vyžádání

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This volume describes recent research in the field of metalloproteinases, in particular their participation in autoimmune diseases such as rheumatoid arthritis.
The work updates current progress in matrix metalloproteinase research, reviewing the latest developments in metalloproteinase inhibitor design and the current status of clinical candidates. It elucidates the structural relationships between different members of the MMP family and provides insight into the contributions of different metalloproteinases to normal and pathological processes. Special emphasis is given to the potential of adamalysins as therapeutic targets.
This volume is intended not only for those active in research into metalloproteinases but also for those with an interest in inflammatory diseases. Thus it addresses both academic and industrial researchers.