Thomas´ Hematopoietic Cell Transplantation, 2 Volume Set

Fully revised, this outstanding reference on bone marrow transplantation is an essential, field–leading resource. In the past four decades, scientific progress in the area has led to an exponential increase in the number of transplant recipients worldwide, and this increase has been paralleled by impressive basic and applied research into the uses of haematopoietic stem cell transplantation. The content systemically covers the scientific basis for stem cell transplantation, patient–related issues, stem cell sources, complications of stem cell transplantation, and allogeneic and autologous transplantation for inherited diseases. Divided into seven sections containing 106 chapters written by international experts, the fifth edition discusses the rapid expansion of the knowledge underlying transplantation biology, increased understanding of the complications of treatment, and new information related to the pathogenesis and treatment of diseases for which transplant is utilized. The edition also covers the expansion of donor options to provide stem cells and the genetic manipulation of both hematopoietic cells of the immune system. The fifth edition: Features over 500 illustrations Has been revised and updated throughout to take account of new and recent developments, from both a scientific and clinical perspective Includes new chapters addressing basic science experiments in stem cell biology, immunology and tolerance Contains expanded content on the benefits and challenges of transplantation, and analysis of the impact of new therapies to help clinical decision–making. Founding editor, E. Donnall Thomas MD, was a pioneer in stem cell research and won the 1990 Nobel Prize for his discoveries concerning organ and cell transplantation in the treatment of human diseases. In continuing this title, the Editors have produced a world–class resource for clinicians and researchers in the field of blood and bone marrow transplantation; hematologists and oncologists; transfusion medicine specialists; and medical staff working within transplant units and teams. Now published in two volumes, the printed book includes a fully searchable Wiley Digital Edition with downloadable figures, linked references, and more!Praise for earlier editions: "A must for the bookshelf of any person who has even the vaguest interest in the biology or practice of marrow, blood, or umbilical–cord hematopoietic stem–cell transplantation." New England Journal of Medicine "Essential addition to the library of any unit performing bone marrow transplants." Journal of Hematotherapy "Uniformly informative, helpful, well–organised and presented, comprehensive, up–to–date and well–referenced." British Journal of Haematology "Overwhelmingly complete, extremely up–to–date and each chapter is written by a world leader in the field." Clinical and Laboratory Haematology