Pharmaceutical Applications of Atomic Spectroscopy

This book emphasizes practical applications of modern atomic spectroscopic techniques across the entire pharmaceutical value chain, including inductively coupled plasma (ICP) optical emission spectroscopy, ICP mass spectrometry, atomic absorption, and laser induced breakdown spectroscopy. This includes both sample preparation and analysis of marketed API and excipients and analytical support of delivery device and container system development as well as process synthesis chemistry. Unique pharmaceutical applications of hyphenated techniques such a HPLC-ICP-MS and laser ablation ICP-MS will also be included. Method validation and regulatory compliance strategies for atomic spectroscopy assays per regional, international and harmonized compendia are also addressed