The use of chemotherapy in the treatment of gynaecologic malignancies has gone through revolutionary changes in the last five years. This state-of-the art text focuses on the general principles of chemotherapeutic agents relative to the diagnosis and treatment of gynecologic cancer. In addition to chemotherapy, the role of hematopoietic growth factors and bone marrow transplantation in the aggressive management of gynaecologic malignancies is also addressed. Other topics covered include the molecular basis of chemotherapy, management of drug toxicity, regional chemotherapy, chemotherapy in pregnancy and cervical, endometrial, and epithelial ovarian cancers, and future research directions.Information is presented in a straightforward manner, making chemotherapy of gynaecologic cancers understandable for all those involved in the treatment of women with these malignancies.