Handbook of Immunohistochemistry and in Situ Hybridization of Human Carcinomas
Molecular Genetics; Lung and Breast Carcinomas
Hayat, M. A.
ISBN: 9780123339416
Vydavatelství: Academic Press
Rok vydání: 2004
Vazba: Hardback
Kategorie: Reference
Počet stran: 556
Dostupnost: Skladem
Původní cena: 7 876 Kč
Výstavní cena:
5 513 Kč(t.j. po slevě 30%)
(Cena je uvedena včetně 10% DPH)
Katalogová cena: 195 GBP
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The various cell types have traditionally been recognized and classified according to their appearance in the light microscope following the process of fixing, processing, sectioning, and staining tissues that is known as histology. Classical histology has been augmented byimmunohistochemistry (the use of specific antibodies to stain particular molecular species in situ). Immunohistochemistry has allowed the identification of many more cell types than could be visualized by classical histology, particularly in the immune system and among the scattered hormone-secreting cells of the endocrine system.This book discusses all aspects of immunohistochemistry and in situ hybridization technologies and the important role they play in reaching a cancer diagnosis. It provides step-by-step instructions on the methods of additional molecular technologies such as DNA microarrays, and microdissection, along with the benefits and limitations of each method. The topics of region-specific gene expression, its role in cancer development and the techniques that assist in the understanding of the molecular basis of disease are relevant and necessary in science today, ensuring a wide audience for this book.