Cancer Chemotherapy & Biotherapy

Thoroughly revised and updated, this book presents a comprehensive, detailed description of the properties and clinical use of anticancer drugs. It provides the latest information on all currently available drugs and biologic agents--their mechanisms of action, interactions with other agents, toxicities, side effects, and mechanisms of resistance. Particular emphasis is placed on the rationale for the use of drugs in specific schedules and combinations, and guidelines are provided for dose adjustment in particular situations. This edition includes new chapters on pharmacology of CNS agents; cancer vaccines; inhibitors of tumor angiogenesis; bisphotphonates; and strategies for drug discovery.