Clinical Studies in Medical Biochemistry, 2nd ed.

This text uses a case-study format to relate the fundamentals of biochemistry to the practice of medicine. cases, carefully selected to cover common diseases and important principles, follow a consistent format. Each chapter begins with a detailed case Report which describes the relevant history, physical findings, and laboratory findings. This is followed by a section on Diagnosis, which includes a brief discussion of differential diagnosis and criteria needed for establishing the diagnosis. The next section, Biochemical Perspectives, forms the heart of each chapter. A discussion of normal metabolic reactions, pathways, and the consequences of the defect is followed by a brief discussion of therapeutic options (Therapy). Each chapter ends with several discussion questions and a brief bibliography.